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Title:
PHARMACEUTICAL COMPOSITION CONTAINING BICYCLIC AMINO-SUBSTITUTED COMPOUND
Document Type and Number:
Japanese Patent JP2004099600
Kind Code:
A
Abstract:

To provide a pharmaceutical composition containing a bicyclic amino-substituted compound, capable of inhibiting production of an inflammatory cytokine.

This pharmaceutical composition contains a compound having general formula (I) (A is a trivalent group, such as pyrimidine and pyrrol, which may be substituted; R1 is an aryl or an heteroaryl of which the each may be substituted; R2 is a heteroaryl which may be substituted; and R3 is indolizine or the like), a pharmacologically acceptable salt thereof, an ester thereof or the other derivative thereof as an active ingredient.


Inventors:
KIMURA TOMIO
OKAWA NOBUYUKI
AOKI KAZUMA
NAKAO AKIRA
NAGASAKI TAKAMI
YAMAZAKI TAKANORI
Application Number:
JP2003199729A
Publication Date:
April 02, 2004
Filing Date:
July 22, 2003
Export Citation:
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Assignee:
SANKYO CO
International Classes:
A61K31/444; A61P1/04; A61P1/16; A61P3/10; A61P9/10; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/10; A61P25/28; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D471/04; C07D491/20; (IPC1-7): A61K31/444; A61P1/04; A61P1/16; A61P3/10; A61P9/10; A61P11/06; A61P13/12; A61P17/06; A61P19/02; A61P19/10; A61P25/28; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D471/04
Attorney, Agent or Firm:
Akio Ohno
Nakata Yasu Male
Toshiaki Yaguchi
Reiko Kanehara
Yuki Echigo