Title:
PHARMACEUTICAL COMPOSITIONS COMPRISING MODIFIED FUCAN FOR USE IN TREATMENT OF FIBROUS ADHESIONS AND OTHER DISORDERS
Document Type and Number:
Japanese Patent JP2016128491
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide pharmaceutical compositions effective in the treatment, prevention, inhibition, or the like of fibrous adhesion, peritonitis, ischemia, reperfusion injury, endotoxinemia, keloid scar, keloid, dermatitis, or rosacea.SOLUTION: The invention provides a pharmaceutical composition containing therapeutically effective amount of fucan with an additive, excipient, base, and diluent, wherein the fucan has a sulphate content between about 14 to 40%w/w; a total carbohydrate content between about 37 to 75%w/w; a molecular weight distribution such that the portion from about 0 to 5,000 g/mol comprises between about 0 to 25%w/w, the portion from about 5,000 to 60,000 g/mol comprises between about 5 to 38%w/w, the portion from about 60,000 to 200,000 g/mol comprises between about 10 to 30%w/w, the portion from about 200,000 to 1,600,000 g/mol comprises between about 8 to 43%w/w, and the portion from more than about 1,600,000 g/mol comprises between about 1 to 33%w/w.SELECTED DRAWING: None
Inventors:
CHRISTOPHER MICHAEL KEVIN SPRINGATE
Application Number:
JP2016019894A
Publication Date:
July 14, 2016
Filing Date:
February 04, 2016
Export Citation:
Assignee:
ARC MEDICAL DEVICES INC
International Classes:
A61K31/737; A61P9/00; A61P9/10; A61P17/00; A61P17/02; A61P29/00; A61P39/02; A61P41/00
Domestic Patent References:
| JP2013500274A | 2013-01-07 |
Attorney, Agent or Firm:
Hiroe Associates Patent Office