To obtain an alkene compound in an improved and generally utilizable way by reacting an organic compound having at least one amino group, hydroxyl group and/or nitrile group with a compound having at least one acetylene group.
The objective compound of the formula R3-HC=CR2-R4 [wherein R2 and R3 are each H, NH2 or a (substituted) 1-20C hydrocarbon which may be interrupted by at least one nonadjacent heteroatom or may have at least one C-C double bond; R4 is R5R6N, R5R6C(Z) or R7O; R5 to R7 are each NH2 or a (substituted) 1-20C hydrocarbon which may be interrupted by at least one nonadjacent heteroatom or may have at least one C-C double bond; R7O is not a 1,2-aminoalkanol; and Z is CN or COOR (wherein R is H or a 1-6C alkyl)] is obtained by reacting (A) an alkene compound of the formula R4-H except 1,2-aminoalkanols with (B) a compound of the formula R2-C≡C-R3 in the presence of (C) CsOH.H2O as one kind of basic catalyst.
HENKELMANN JOCHEM DR
PREISS THOMAS DR
KNOCHEL PAUL
TZALIS DIMITRIOS
KORADIN CHRISTOPHER
