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Title:
PROPIONIC ACID DERIVATIVE EFFECTIVE IN TREATING LIPID DISORDER
Document Type and Number:
Japanese Patent JP2006298925
Kind Code:
A
Abstract:

To provide a new compound effective in treating clinical conditions including lipid disorders (dyslipidemias), whether or not associated with insulin resistance, and other symptom of a metabolic syndrome.

The new compound is a new 3-[amino-oxy(alkyl, alkyloxy and alkylthio)phenyl]-propionic acid derivative (e.g. 3-(4-{2-[(2,4-difluorobenzyl)(octyl)amino]-2-oxoethoxy}phenyl)-2-ethoxypropionic acid), and its optical isomers and racemic body, these provide pharmaceutically acceptable salts, prodrugs, solvated materials, and crystallized products.


Inventors:
LI LANNA
ALSTERMARK EVA-LOTTE LINDSTEDT
OLSSON CHRISTINA
Application Number:
JP2006139673A
Publication Date:
November 02, 2006
Filing Date:
May 19, 2006
Export Citation:
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Assignee:
ASTRAZENECA AB
International Classes:
C07C235/06; A61K31/195; A61K31/44; A61K31/496; A61K49/04; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P13/12; A61P15/08; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07C233/11; C07C233/51; C07C235/08; C07C235/20; C07C235/22; C07C235/24; C07C255/46; C07C309/66; C07C323/41; C07C323/56; C07D209/14; C07D295/135; C07D295/185; C07D317/58; C07D333/20; A61K31/192; A61K31/255; A61K31/275; A61K31/36; A61K31/381; A61K31/4045
Domestic Patent References:
JPH10287634A1998-10-27
JP2006527730A2006-12-07
Foreign References:
WO2001053267A12001-07-26
WO2002038553A22002-05-16
WO2004000789A12003-12-31
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita