Title:
ピラゾール誘導体化合物及びその用途
Document Type and Number:
Japanese Patent JP7181287
Kind Code:
B2
Abstract:
Provided is a compound represented by Formula 1 having an inhibitory activity on lysine-specific demethylase-1 (LSD1), an optical isomer, a solvate, a tautomer, or a pharmaceutically acceptable salt thereof, which is effective in preventing or treating a disease caused by abnormal activation of LSD1.
Inventors:
Infan Pe
The Suk Kim
Won Joo Eun Kim
Chang Hee Park
The Yong Sung
Yong Gil Ann
The Suk Kim
Won Joo Eun Kim
Chang Hee Park
The Yong Sung
Yong Gil Ann
Application Number:
JP2020515066A
Publication Date:
November 30, 2022
Filing Date:
September 13, 2018
Export Citation:
Assignee:
Hanmi Pharmaceuticals Company Limited
International Classes:
C07D231/14; A61K9/06; A61K9/107; A61K9/14; A61K9/20; A61K9/48; A61K31/437; A61K31/438; A61K31/439; A61K31/454; A61K31/4545; A61K31/4709; A61K31/496; A61K31/55; A61K45/00; A61P35/00; A61P43/00; C07D401/06; C07D401/14; C07D403/06; C07D405/14; C07D417/14; C07D451/04; C07D471/04; C07D471/08; C07D471/10
Domestic Patent References:
| JP3141261A | ||||
| JP2017521407A | ||||
| JP2017502940A |
Foreign References:
| US20140107157 | ||||
| US20040192667 | ||||
| WO2005063737A1 | ||||
| WO2006133926A1 | ||||
| WO2007046550A1 | ||||
| AU2004200420A1 | ||||
| WO2017090756A1 |
Other References:
Bioorganic & Medicinal Chemistry Letters,2011年,21,4913-4918
Bioorganic & Medicinal Chemistry Letters,2011年,21,562-568
Bioorganic & Medicinal Chemistry Letters,2017年05月24日,27,3521-3528
Bioorganic & Medicinal Chemistry Letters,2011年,21,562-568
Bioorganic & Medicinal Chemistry Letters,2017年05月24日,27,3521-3528
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe