βアドレナリン受容体キナーゼ1のインヒビターとしてのピラゾロピリジン誘導体

Title:

βアドレナリン受容体キナーゼ1のインヒビターとしてのピラゾロピリジン誘導体

Document Type and Number:

Japanese Patent JP5010594

Kind Code:

B2

Abstract:

The invention relates to 6-amido substituted pyrazolopyridine derivatives of the formula (I) useful as inhibitors of beta-adrenergic receptor kinase 1 (βARK-1), compositions containing such compounds and their use for the treatment and prevention of chronic heart failure, hypertension, myocardial ischemia and hepatitis C virus (HCV) infections, and for the prevention of opiate addiction.

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Inventors:

Henning Steinhagen
Jochen Hoover
Kurt Ritter
Bernard Pilart
Kirsten Björgarde
Marcel Partech
Martin Sumulcina
Linri Way

Application Number:

JP2008518660A

Publication Date:

August 29, 2012

Filing Date:

June 13, 2006

Export Citation:

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Assignee:

SANOFI

International Classes:

C07D471/04; A61K31/437; A61K31/444; A61K31/4545; A61K31/5377; A61P9/04; A61P9/10; A61P9/12; A61P25/36; A61P31/12; A61P43/00

Domestic Patent References:

JP200220386A

Foreign References:

WO1999030710A1
WO2004076450A1

Attorney, Agent or Firm:

Chika Takagi
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi

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