Title:
QUINOLINONE DERIVATIVE AS TYROSINE KINASE INHIBITOR
Document Type and Number:
Japanese Patent JP2014129378
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a variety of chemicals to provide VEGF-RTK-antagonist therapies.SOLUTION: Organic compounds having the structural formulas (I) and (II) are provided where the variables have the values described in the specification. Pharmaceutical formulations include the organic compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and may be prepared by mixing the organic compounds or pharmaceutically acceptable salts of the organic compounds with a carrier and water. A method of treating a patient includes administering a pharmaceutical formulation according to the invention to a patient in need of treatment.
Inventors:
RENHOWE PAUL
PECCHI SABINA
MACHAJEWSKI TIM
SHAFER CYNTHIA
TAYLOR CLARKE
MCCREA BILL
MCBRIDE CHRIS
JAZAN ELISA
PECCHI SABINA
MACHAJEWSKI TIM
SHAFER CYNTHIA
TAYLOR CLARKE
MCCREA BILL
MCBRIDE CHRIS
JAZAN ELISA
Application Number:
JP2014032859A
Publication Date:
July 10, 2014
Filing Date:
February 24, 2014
Export Citation:
Assignee:
NOVARTIS VACCINES & DIAGNOSTIC
International Classes:
C07D243/08; A61K31/19; C07D401/04; A61K31/4709; A61K31/4745; A61K31/496; A61K31/513; A61K31/5377; A61K31/541; A61K31/551; A61P35/00; A61P43/00; C07D401/14; C07D403/04; C07D405/04; C07D405/14; C07D409/04; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D453/02; C07D471/04; C07D487/08; C07D519/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita