細胞小器官内のグルタチオン測定用リアルタイム蛍光イメージングセンサおよびその製造方法

Japanese Patent JP7169004

B2

The present invention relates to a real-time fluorescence imaging sensor for measuring glutathione in cell organelles and a method for fabricating the same. More specifically, the present invention relates to a novel compound for measuring glutathione in cell organelles, a method for preparing the novel compound, a real-time fluorescence imaging sensor for measuring glutathione in cell organelles, which comprises the novel compound, a method for fabricating the imaging sensor, and a method of measuring glutathione in cell organelles by use of the imaging sensor.When the composition comprising the compound according to the present invention is used, it can measure the antioxidant activity of the organelle mitochondria or Golgi apparatus in living cells, particularly stem cells, and can screen highly active stem cells based on the results obtained by measuring the antioxidant activity of the cell organelle.

JPS58170724	SUBSTITUTED HEXAHYDROPYRROLO(1,2-A)-QUINOLINE, HEXAHYDRO-1H-PYRIDO(1,2-A)-QUINOLINE, HEXAHYDROBENZO (E)-INDENE AND OCTAHYDROPHENANTHRENE AND THEIR COMPOSITION
JP2005320338	VISIBLE LIGHT PHOTOSENSITIVE RESIN COMPOSITION AND ITS APPLICATION
WO/2003/091257	[1,4]DIAZOCINO [7,8,1-hi]INDOLE DERIVATIVES AS ANTIPSYCHOTIC AND ANTIOBESITY AGENTS

Kang, Huns
Kim, Hae Mi
Song, Ji Eun
Kim, Myung Jin
Choi, Gi Han

JP2020511502A

November 10, 2022

August 23, 2018

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CELL2IN, INC.

C07D491/16; C07F9/6561; C09B57/02; C12Q1/02; G01N21/64; G01N33/15; G01N33/50

KR1020160059978A
CN103820104A
US20170007723

REGISTRY(STN)[online],2001.12.07CAS登録番号 374544-06-6
Cho, A. Young; Choi, Kihang,A coumarin-based fluorescence sensor for the reversible detection of thiols,Chemistry Letters ,2012年,41(12),1611-1612

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