Title:
RECOVERY OF CEPHALOSPORINE C
Document Type and Number:
Japanese Patent JPS54101490
Kind Code:
A
Abstract:
A process for the recovery of cephalosporin C comprises (a) contacting a fermentation broth containing cephalosporin C with an anion exchange resin which is either a weak-base resin in the weak acid salt form or free base form or a strong-base resin in the weak acid salt form, to obtain a weakly acidic percolate containing said cephalosporin C from which anions of strong acids present in said broth have been removed; (b) contacting said percolate with a strong cation exchange resin in the acid form, whereby cations in said resulting solution are replaced by protons and said cephalosporin C remains in the substantially deionized percolate; and (c) adsorbing cephalosporin C from said percolate onto a weak-base anion exchange resin.
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Inventors:
HARII KAASON SUTEIIBURUZU
KENESU BURITSUGUSU
KENESU BURITSUGUSU
Application Number:
JP14974478A
Publication Date:
August 10, 1979
Filing Date:
December 05, 1978
Export Citation:
Assignee:
GLAXO GROUP LTD
International Classes:
C07D501/12; C07D501/28; C12P35/06; (IPC1-7): C12D9/02