Title:
RIBONUCLEOSIDE H-BORANOPHOSPHONATE
Document Type and Number:
Japanese Patent JP2011184318
Kind Code:
A
Abstract:
To provide a ribonucleoside H-boranophosphonate compound useful for efficiently synthesizing boranophosphate and other modified RNAs containing phosphorus-boron bonds.
The ribonucleoside H-boranophosphonate represented by formula (I) (wherein R1 and R2 each independently represents hydrogen atom or a protective group of hydroxy group; and Bs represents nucleic acid base optionally having a protective group) or a salt thereof is provided.
Inventors:
WADA TAKESHI
HIURA SHINGO
HIURA SHINGO
Application Number:
JP2010048823A
Publication Date:
September 22, 2011
Filing Date:
March 05, 2010
Export Citation:
Assignee:
UNIV TOKYO
International Classes:
C07H23/00
Domestic Patent References:
| JPH10204097A | 1998-08-04 |
Foreign References:
| WO2005085272A1 | 2005-09-15 |
Other References:
JPN6014027033; Ｃｈｅｍ． Ｃｏｍｍｕｎ． , 20090219, Ｐ２４６６-２４６８
JPN6014027034; Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｖ１６, 2008, Ｐ９１５４-９１６０
JPN6014027034; Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｖ１６, 2008, Ｐ９１５４-９１６０
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes