To obtain the subject new compound capable of being synthesized by using an inexpensive secondary raw material without a complicated purification step and useful as an intermediate for an aromatic amidine derivative having anticoagulant actions based on excellent inhibiting actions on an activated blood coagulation factor X.
This salt is formed from a compound represented by formula 1 {Ra is hydrogen or an alkoxyl; Rb is hydrogen, an alkyl or the like; Rc is hydrogen, carboxyl or the like; Rd is hydrogen, amino or the like; (n) is 0-4; A is a 1-4C alkylene, formula II [B is an alkylene or carbonyl ; Re is hydrogen a group represented by the formula; D-W-Rf (D is solfo or the like; W is a single bond or the like; Rf is hydroxyl group or the like)]; X is a single bond, oxygen or the like; Y is an (un)saturated 5- to 6-membered heterocyclic group, amino or the like; formula III is indolyl, naphthyl or the like} and benzoic acid, e.g. ethyl (2S)-3-(7-amidino-2-naphthyl)-2-[4-[((3S)-3-pyrrolidinyl) oxy]phenyl]propionate dibenzoate. The salt is obtained by reacting the compound represented by formula I with the benzoic acid.
MAKINO TORU
YOKOYAMA YUKIO
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