PURPOSE: To obtain a compound useful as a synthetic intermediate for an N- substituted phenyl-3,4,5,6-tetrahydrophthalimide derivative having excellent herbicidal activities.
CONSTITUTION: This compound of formula I (R1 is a 1-6C alkyl; X is a halogen; Y is H, nitro or amino), e.g. 2-chloro-4-fluorophenyl(isobutyl) carbonate. The compound of formula I is obtained by reacting 2-chloro-4-fluorophenol of formula II with an alkyl chloroformate (e.g. isobutyl chloroformate). A nitrobenzene derivative is further obtained by subsequently nitrating the resultant compound with fuming nitric acid, etc. The prepared nitrobenzene derivative is reduced in the presence of hydrogen by using a Pd/C catalyst to afford an aniline derivative. An N-substituted phenyl-3,4,5,6-tetrahydrophthalimide derivative has high herbicidal effects in a low dose and hardly causes the phytotoxicity to main crops.
YAMASHITA MITSUO
TATENO TOMOKO
EJIRI EMIKO
HARASAWA KIKUKO
ONCHI YUICHI
UKAI SADAYUKI
NAGATO SHOIN
CHISSO CORP
KAKEN PHARMA CO LTD
| JPS63310855A | 1988-12-19 | |||
| JPS63183501A | 1988-07-28 | |||
| JPS61501032A | 1986-05-22 | |||
| JPH04210984A | 1992-08-03 |