Title:
置換ピペリジン類、およびヒスタミンH3受容体に関連した疾患の治療のためのその使用
Document Type and Number:
Japanese Patent JP2005508986
Kind Code:
A
Abstract:
The present invention relates to novel substituted imidazoles, to the use of these compounds as medicaments, to pharmaceutical compositions comprising the com-pounds, and to a method of treatment employing these compounds and compositions. The present compounds show a high and selective binding affinity to the histamine H3 receptor indicating a histamine H3 receptor antagonistic or agonistic io activity. As a result, the compounds are useful for the treatment of disorders related to the histamine H3 receptor. More particularly, the present compounds possess a histamine H3 receptor agonistic activity and are accordingly useful in the treatment of disorders in which a histamine H3 receptor activation is beneficial.
Inventors:
Rudolph, Claus
Hanaus, Rudolph
Stenkampu, Dirk
Muller, Stephan
Christo, Bernd
Hanaus, Rudolph
Stenkampu, Dirk
Muller, Stephan
Christo, Bernd
Application Number:
JP2003542152A
Publication Date:
April 07, 2005
Filing Date:
November 05, 2002
Export Citation:
Assignee:
NOVO NORDISK AKTIE SELSXAB
International Classes:
A61K31/4164; A61K31/4245; A61K31/427; A61K31/428; A61K31/4375; A61K31/4439; A61K31/4709; A61P1/04; A61P9/06; A61P9/10; A61P11/02; A61P11/06; A61P25/04; A61P37/08; A61P43/00; C07D233/54; C07D233/64; C07D271/06; C07D277/24; C07D401/12; C07D405/12; C07D413/12; C07D417/12; C07D471/04; (IPC1-7): C07D233/64; A61K31/4164; A61K31/4245; A61K31/427; A61K31/428; A61K31/4375; A61K31/4439; A61K31/4709; A61P1/04; A61P9/06; A61P9/10; A61P11/02; A61P11/06; A61P25/04; A61P43/00; C07D401/12; C07D405/12; C07D413/12; C07D417/12; C07D471/04
Attorney, Agent or Firm:
Takehiko Suzue
Satoshi Kono
Makoto Nakamura
Sadao Muramatsu
Ryo Hashimoto
Satoshi Kono
Makoto Nakamura
Sadao Muramatsu
Ryo Hashimoto
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