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Title:
診断適用のための超常磁性および高多孔性ポリマー粒子
Document Type and Number:
Japanese Patent JP7100663
Kind Code:
B2
Abstract:
The present disclosure relates to magnetic particles, wherein each particle has a polymer matrix and at least one magnetic core (M), wherein the polymer matrix has at least one crosslinked polymer and wherein the magnetic particle has a particle size in the range of from 1 to 60 micrometer. Further, the present disclosure relates to a method of preparing such particles, and to particles obtainable or obtained by said method. Moreover, the present disclosure uses these magnetic particles for qualitative and/or quantitative determination of at least one analyte in a fluid. Further, the present disclosure relates to a method for determining at least one analyte in a fluid sample using the contacting of a magnetic particle of the disclosure or a magnetic particle obtained by the method of the present disclosure with a fluid sample having or suspected to have the at least one analyte.

Inventors:
Bole, Jens Christian
Silvestre, Martin Eduardo
Hook, Stephan
Builder, Caroline
Application Number:
JP2019555761A
Publication Date:
July 13, 2022
Filing Date:
April 12, 2018
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
G01N33/553; G01N33/50; G01N33/543; G01N33/545
Domestic Patent References:
JP11510836A
Foreign References:
US20150212095
Other References:
V. V. Tolmacheva et al.,Magnetic Adsorbents Based on Iron Oxide Nanoparticles for the Extraction and Preconcentration of Organic Compounds,Journal of Analytical Chemistry,2016年,Vol.71, No.4,pp.321-338
Yan Ma et al.,Preparation of a novel magnetic microporous adsorbent and its adsorption behavior of p-nitrophenol and chlorotetracycline,Journal of Hazardous Materials,2014年,Vol.266,pp.84-93
Liangxiao Tan and Bien Tan,Hypercrosslinked porous polymer materials: design, synthesis, and applications,Chem. Soc. Rev.,2017年,Vol.46,pp.3322-3356
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Tsurukuro Toshitaka