Title:
エストロゲン受容体を介する軟骨破壊の抑制
Document Type and Number:
Japanese Patent JP2005524630
Kind Code:
A
Abstract:
The present invention relates to the pharmaceutical use of selective estrogen receptor modulators SERMs alone or in combination with progestins for the treatment or prevention of diseases associated with elevated cartilage degradation. In particular this invention relates to the pharmaceutical use of chroman derivatives in combination with moretindrone for the treatment or prevention of osteoarthritis or rheumatoid arthritis.
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Inventors:
Christiansen, Claus
Christoph, Stephan
Christoph, Stephan
Application Number:
JP2003563549A
Publication Date:
August 18, 2005
Filing Date:
January 13, 2003
Export Citation:
Assignee:
NORDIC BIOSCIENCE A/S
International Classes:
C07D405/12; A61K31/138; A61K31/353; A61K31/37; A61K31/40; A61K31/4535; A61K31/567; A61K31/568; A61K31/57; A61K31/573; A61P3/04; A61P5/00; A61P9/00; A61P13/02; A61P15/00; A61P17/14; A61P19/02; A61P19/10; A61P25/00; A61P27/12; A61P29/00; A61P35/00; C07J5/00; C07J7/00; (IPC1-7): A61K31/40; A61K31/567; A61K31/568; A61K31/57; A61K31/573; A61P3/04; A61P5/00; A61P9/00; A61P13/02; A61P15/00; A61P17/14; A61P19/02; A61P19/10; A61P25/00; A61P27/12; A61P29/00; A61P35/00; C07D405/12; C07J5/00; C07J7/00
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Arihara Koichi
Matsushima Tetsuo