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Title:
TECHNIQUES FOR NEUROMODULATION
Document Type and Number:
Japanese Patent JP2022169606
Kind Code:
A
Abstract:
To provide, generally, techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue to alter activity at a synapse between a neuronal cell and a non-neuronal cell.SOLUTION: A modulation system comprises: an energy application device configured to apply energy to a region of interest of a tissue in a subject, the tissue comprising a plurality of axon terminals of respective neurons, the axon terminals forming axoextracellular synapses between individual axon terminals and respective non-neuronal cells; and a controller configured to spatially select the region of interest of the tissue, the region of interest comprising a subset of the plurality of axon terminals and an associated subset of the axoextracellular synapses.SELECTED DRAWING: Figure 1

Inventors:
Pleo, Christopher Michael
Kotero, Victoria
Fan, ing
Carne Mare, Sirisha
Wallace, Kirk Dennis
Rigby, Kenneth Waine
Hank, Iriana
Rossman, james
Khao, Tzu Jen
Mills, David
Ashe, Jeffrey
Application Number:
JP2022125965A
Publication Date:
November 09, 2022
Filing Date:
August 06, 2022
Export Citation:
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Assignee:
GENERAL ELECTRIC COMPANY
International Classes:
A61B18/00; A61B5/055; A61B10/00; A61N7/00; G01T1/161
Domestic Patent References:
JP2019534090A2019-11-28
JP2013507198A2013-03-04
JP2011527931A2011-11-10
Foreign References:
WO2016090175A12016-06-09
US20120065494A12012-03-15
US20110118600A12011-05-19
Attorney, Agent or Firm:
Kazuya Sekiguchi