Title:
ヒトの血液網膜関門の一時的な破綻、および網膜障害の治療のためのそれらの使用
Document Type and Number:
Japanese Patent JP7199379
Kind Code:
B2
Abstract:
The present invention relates to an ultrasound contrast agent for use in treating a retina disorder by transiently disrupting the blood-retinal barrier (BRB) of a human, wherein the ultrasound contrast agent is administered just before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam. The present invention further relates to a therapeutically active agent for use in treating a retina disorder in a human, wherein the therapeutically active agent is to be delivered in combination with an ultrasound contrast agent, which is administered before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam in order to transiently disrupting the blood-retinal barrier (BRB) of the human, to allow the therapeutically active agent to cross the BRB and to target the retina. The present invention also relates to an eye ultrasound delivery device that may be used to treat a retina disorder.
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Inventors:
Alexander Carpentier
Application Number:
JP2019560346A
Publication Date:
January 05, 2023
Filing Date:
May 04, 2018
Export Citation:
Assignee:
SORBONNE UNIVERSITE
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
International Classes:
A61F9/007; A61N7/00
Domestic Patent References:
| JP2019516534A | ||||
| JP2013536187A |
Foreign References:
| WO2018071839A1 | ||||
| WO2013149260A1 |
Attorney, Agent or Firm:
Yamato Kento
Junko Yamada
Junko Yamada
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