Title:
ケモカイン受容体活性のテトラヒドロピラニルシクロペンチルベンジルアミド調節剤
Document Type and Number:
Japanese Patent JP2006514003
Kind Code:
A
Abstract:
The present invention is directed to compounds of the formula (I) (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R27, R28, R29, R30, R31, X, m, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2
Inventors:
Bootla, gabor
Mills, Thunder Gi
Alexander Pasternak
Siyan Karan, Kosanda Raman
Yang, Lifou
Chiyo, Chiyan Yu
Goble, Stephen Day
Mills, Thunder Gi
Alexander Pasternak
Siyan Karan, Kosanda Raman
Yang, Lifou
Chiyo, Chiyan Yu
Goble, Stephen Day
Application Number:
JP2004550126A
Publication Date:
April 27, 2006
Filing Date:
October 24, 2003
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07C237/24; A61K31/00; A61K31/16; A61K31/215; A61K31/335; A61K31/337; A61K31/341; A61K31/343; A61K31/35; A61K31/351; A61K31/352; A61K31/353; A61K31/357; A61K31/381; A61K31/382; A61K31/407; A61K31/41; A61K31/4162; A61K31/4196; A61K31/427; A61K31/436; A61K31/4409; A61K31/453; A61K31/5383; A61P9/10; A61P19/02; A61P29/00; A61P37/02; A61P37/08; A61P43/00; C07D211/58; C07D211/96; C07D305/08; C07D307/14; C07D307/22; C07D307/93; C07D309/08; C07D309/10; C07D309/14; C07D311/00; C07D311/02; C07D311/68; C07D311/74; C07D311/94; C07D313/04; C07D319/06; C07D333/36; C07D335/02; C07D405/04; C07D405/12; C07D409/12; C07D417/12; C07D491/04; C07D491/052; C07D493/08; C07D498/04
Domestic Patent References:
| JP2002528490A | 2002-09-03 | |||
| JPH11510803A | 1999-09-21 | |||
| JP2005532308A | 2005-10-27 |
Foreign References:
| WO2001087866A1 | 2001-11-22 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura