To provide a thermal transfer sheet having stable transference releasability which is not influenced by an illumination light source even compared with a pigment colorant and a printed matter, excellent in dot sharpness by transferring of a colorant membrane, has excellent sensitivity, and suppresses film covering.

In this thermal transfer sheet wherein a photothermal conversion layer containing at least a photothermal conversion substance and an image forming layer are provided on a supporting body in this order, an absolute value of differential of a solubility parameter (SP value) between a binder in the image forming layer and a binder contained in the lower layer which are concluded by an OKITSU method is more than 1.5.