Title:
【発明の名称】9,10- セコ-エストラン - ユウドウタイノ セイホウ
Document Type and Number:
Japanese Patent JPS5848526
Kind Code:
B2
Abstract:
6,9-Oxido-9,10-seco-1,3,5(10),6,8,14-estrahexaenes, useful as intermediates in the total synthesis of steroids, of the formula WHEREIN N IS 1 OR 2, R1 is lower-alkyl, R2, R 3 and R4 are H, alkoxy or acyloxy, X is a free or ketalized keto or free, esterified or etherified hydroxymethylene, are produced by the cyclization, with an acid catalyst, of a 9,10-secoestrane of the formula WHEREIN R1, R2, R3, R4, X and n have the values given above, and Q is carbonyl or dialkoxymethylene. Hydrogenation produces the corresponding 6,9-oxido-9,10-seco-1,3,5(10)-estratrienes and 9-oxy-9,10-seco-1,3,5(10)-estratrienes.
Inventors:
URURITSUHI EEDERU
GUREGOORU HATSUFUERU
YURUGEN RUTSUPERUTO
GERUHARUTO ZAUERU
RUUDORUFU UIIHIERUTO
GUREGOORU HATSUFUERU
YURUGEN RUTSUPERUTO
GERUHARUTO ZAUERU
RUUDORUFU UIIHIERUTO
Application Number:
JP12036873A
Publication Date:
October 28, 1983
Filing Date:
October 25, 1973
Export Citation:
Assignee:
SCHERING AG
International Classes:
C07C69/16; B01J27/00; B01J31/00; C07B61/00; C07C27/00; C07C29/132; C07C29/136; C07C35/23; C07C41/00; C07C43/168; C07C43/178; C07C43/18; C07C43/196; C07C43/20; C07C43/23; C07C45/00; C07C49/675; C07C49/84; C07C67/00; C07D307/77; C07D319/08; C07J1/00; C07J51/00; (IPC1-7): C07C35/23; C07C43/196; C07C43/23; C07C69/16; C07D319/08
Attorney, Agent or Firm:
Toshio Yano