Title:
【発明の名称】抗ウィルス性ジベンゾチアゼピノン誘導体
Document Type and Number:
Japanese Patent JPH06506930
Kind Code:
A
Abstract:
PCT No. PCT/GB92/00805 Sec. 371 Date Dec. 6, 1993 Sec. 102(e) Date Dec. 6, 1993 PCT Filed May 1, 1992 PCT Pub. No. WO92/19277 PCT Pub. Date Nov. 12, 1992 (I) Compounds of formula (I) wherein n is 0, 1 or 2; and R1 and R2, which may be the same or different, each represent one or more ring substituent(s) selected from: hydrogen, hydroxy, halogen, cyano, nitro, C1-6alkyl, C3-6cycloalkyl or C1-6alkoxy (where the alkyl or cycloalkyl moiety may be optionally substituted by one or more substituents selected from halogen atoms and hydroxyl groups); -NR4R5 where R4 and R5, which may be the same or different, each represent hydrogen or C1-6alkyl; -S(O)mR6, where m is 0, 1, 2 or 3 and R6 represents hydrogen, C1-6alkyl or C3-6cycloakyl; -SO2NR4R5 where R4 et R5 are each as defined above; phenyl, phenylC1-3alkoxy or phenylC1-3alkyl where the phenyl group may be optionally substituted by one or more substituents independently selected from C1-6alkyl, C1-6alkoxy, hydroxy, nitro, halogen and amino; and -CO2H or -COR7 where R7 is C1-6alkyl or C3-6cycloalkyl; R3 represents hydrogen or C1-4alkyl; and esters, salts and other physiologically functional derivatives thereof; show activity as antiviral agents, for example against HIV. Certain of the compounds are novel.
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Inventors:
Nicole, Robin, Hamish
Slater, martin, john
Hodgson, Simon, Teen Bee
Slater, martin, john
Hodgson, Simon, Teen Bee
Application Number:
JP50865892A
Publication Date:
August 04, 1994
Filing Date:
May 01, 1992
Export Citation:
Assignee:
THE WELLCOME FOUNDATION LIMITED
International Classes:
A61K31/55; A61K31/554; A61P31/12; C07D281/16; (IPC1-7): C07D281/16; A61K31/55
Attorney, Agent or Firm:
Akira Asamura (3 outside)