【発明の名称】細胞増殖阻害剤

Japanese Patent JP3497504

B2

PCT No. PCT/GB91/01898 Sec. 371 Date Apr. 30, 1993 Sec. 102(e) Date Apr. 30, 1993 PCT Filed Oct. 30, 1991 PCT Pub. No. WO92/07938 PCT Pub. Date May 14, 1992Non-agglutinating beta -galactoside binding proteins (GBP), both the natural proteins and proteins produced by recombinant DNA technology, are provided for use as inhibitors and regulators of vertebrate cell growth and as anti-viral agents. Methods of producing the GBP's are also described. The GBP's show a powerful growth inhibitory effect against human cancer cells making them potentially useful therapeutic agents in the treatment of malignant disease and also show an inhibitory effect on viral replication making them potentially useful as anti-viral agents.

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Multi, libio
Wells, Valerie

JP51773391A

February 16, 2004

October 30, 1991

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Multi, libio
Wells, Valerie

A61P31/12; A61P35/00; A61P37/00; C07K1/20; C07K1/22; C07K14/00; C07K14/42; A61K38/00; C07K14/47; C07K14/475; C07K16/18; C07K19/00; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/02; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; A61K38/00; A61P31/12; A61P35/00; A61P37/00; C07K14/47; C12P21/02

Ｊｕｎ ＨＩＲＡＢＡＹＡＳＨＩ ｅｔ ａｌ，ＣＯＭＰＬＥＴＥ ＡＭＩＮＯ ＡＣＩＤ ＳＥＱＥＮＣＥ ＯＦ Ａ Ｂ−ＧＡＬＡＣＴＯＳＩＤＥ−ＢＩＮＤＩＮＧ ＬＥＣＴＩＮ ＦＲＯＭ ＨＵＭＡＮ ＰＬＡＣＥＮＴＡ，Ｊ．ＢＩＯＣＨＥＭ．，Ｖｏｌ．１０４，Ｎｏ．１，ｐａｇｅｓ１−４，１９８８
Ｔ．Ｊ．Ｇｒｅｅｒ．ＷＩＬＳＯＮ ｅｔ ａｌ，ＴＨＥ ＳＥＱＵＥＮＣＥ ＯＦ ＴＨＥ ＭＯＵＳＥ １４ｋＤａ Ｂ−ＧＡＬＡＣＴＯＳＩＤＥ−ＢＩＮＤＩＮＧ ＬＥＣＴＩＮ ＡＮＤ ＥＶＩＤＥＮＣＥ ＦＯＲ ＩＴＳ ＳＹＮＴＨＥＳＩＳ ＯＮ ＦＲＥＥ ， ＢＩＯＣＨＥＭ．Ｊ．，Ｖｏｌ．２６１，ｐａｇｅｓ ８４７−８５２，１９８９

Aoyama Ryo (1 person outside)

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