Title:
【発明の名称】エリスロポエチンイソフォーム
Document Type and Number:
Japanese Patent JP2983629
Kind Code:
B2
Abstract:
Continuation in part of U.S. application no. 421,444 filed 13 October 1989. Erythropoietin isoforms claimed are produced by expression of exogenous DNA in a non-human eukaryotic host cell. They contain amino acids 1-165 or 1-166 of natural human erythropoietin. The isoforms pref. contain 1-14 sialic acid gps. (esp. 9-14 gps.) per erythropoietin molecule. Use of the isoforms and their mixts. are also claimed comprising subjecting a purified erythropoietin to isoelectric focussing and eluting a single isoform from the gel. Specifically claimed erythropoietin analogues are (Asn69) EPO,(Asn125,Ser127) EPO,(Thr125) EPO and (Pro124,Thr125) EPO.
More Like This:
| JP2964290 | MINERAL ABSORPTION PROMOTER |
| JPH01110621 | LIPOSOME TRANSPORTATION-RELEASE SYSTEM OF OPIOID ANALGESIC |
| WO/1994/020079 | HUMAN BRAIN PHOSPHODIESTERASE |
Inventors:
SUTORITSUKURANDO TOOMASU UEIN
BAAN TOOMASU EDOWAADO
ERIOTSUTO SUTEIIBUN JOOJI
BAAN TOOMASU EDOWAADO
ERIOTSUTO SUTEIIBUN JOOJI
Application Number:
JP51456890A
Publication Date:
November 29, 1999
Filing Date:
October 09, 1990
Export Citation:
Assignee:
KIRIN AMUJEN INC
International Classes:
A61K31/00; A61K38/17; A61K38/22; A61P7/00; C07H21/04; C07K14/505; C07K1/26; C07K14/00; C07K14/52; C07K14/575; C12N5/00; C12N5/10; C12N15/09; C12N15/16; C12N15/18; C12P21/00; C12P21/02; A61K38/00; C12R1/19; C12R1/91; C07K; (IPC1-7): C12N15/09; A61K31/00; A61K38/22; C07K14/505; C12P21/02
Domestic Patent References:
| JP63503352A |
Other References:
Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ，２４９（１３）（１９７４），Ｐ．４２０２−４２０６
Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ，２６２（２５）（１９８７），Ｐ．１２０５９−１２０７４
Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｌｏｇｉｃａｌ Ｃｈｅｍｉｓｔｒｙ，２６２（２５）（１９８７），Ｐ．１２０５９−１２０７４
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)