【発明の名称】イソプレノイドホスホリパーゼ▲A2▼阻害剤およびそれを包含する製剤

Title:

【発明の名称】イソプレノイドホスホリパーゼ▲A2▼阻害剤およびそれを包含する製剤

Document Type and Number:

Japanese Patent JP2943089

Kind Code:

B2

Abstract:

Compounds of the formula wherein R1 is CH=CY-C(CH3)=CHX wherein X and Y are different and each is of the formula wherein R' and R'' independently are H or alkyl of C1-6 and R1 includes all possible geometric isomers. are demonstrated effective in treating inflammation, both topically and internally. The mechanism appears to be the inhibition of phospholipase A2 enzymes.

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Inventors:

EFU AIBII KYARORU
ANITA RUUIN
KENESU TORANHOTSUSHU
SUTEFUEN EI SUTEINAA

Application Number:

JP31302191A

Publication Date:

August 30, 1999

Filing Date:

September 20, 1991

Export Citation:

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Assignee:

BURISUTORU MAIYAAZU SUKUIBU CO

International Classes:

A61K31/19; A61K31/00; A61K31/20; A61K31/202; A61K31/203; A61K31/23; A61K31/235; A61P17/00; A61P29/00; C07C63/64; C07C63/66; C07C69/78; C07C403/20; C12N9/99; (IPC1-7): C07C403/20; A61K31/00; A61K31/20; A61K31/235; C12N9/99

Domestic Patent References:

JP4500824A
JP4501122A

Attorney, Agent or Firm:

Takehiko Saito

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