Title:
【発明の名称】テクネチウム放射性薬剤の新しいコア
Document Type and Number:
Japanese Patent JP3341001
Kind Code:
B2
Abstract:
Novel complexes of technetium (<99>Tc or <99m>Tc) which contain the moiety Tc=NR, Tc-N=NY or Tc(-N=NY)2, and a ligand which confers biological target-seeking properties on the complex, wherein R represents an aryl group, a substituted or unsubstituted alkyl group, or the grouping =NR<1>R<2>; Y represents an aryl group or a substituted or unsubstituted alkyl group; and R<1> and R<2> are hydrogen, aryl groups or substituted or unsubstituted aliphatic or cyclic alkyl groups, and may be both the same or different, provided that both are not hydrogen. The complexes are suitable for use in radiopharmaceuticals for a variety of clinical applications. Methods for the preparation of these technetium complexes are also described.
Inventors:
Archer, Colin Mill
Dilworth, Jonathan Robin
Jovan Btra, Pana
Rutherm Ian Andrew
Russell Martin, Thompson
Dilworth, Jonathan Robin
Jovan Btra, Pana
Rutherm Ian Andrew
Russell Martin, Thompson
Application Number:
JP2001197466A
Publication Date:
November 05, 2002
Filing Date:
May 25, 2001
Export Citation:
Assignee:
Amersham International PLC
International Classes:
A61K49/00; A61K51/04; C07F9/50; C07F13/00; C07F19/00; A61K51/00; (IPC1-7): C07F13/00; A61K51/00; C07F19/00
Domestic Patent References:
| JP152787A |
Attorney, Agent or Firm:
Kazuo Shamoto (4 outside)