Title:
【発明の名称】蛋白質の放射性標識用の放射性核種金属キレート
Document Type and Number:
Japanese Patent JPH04500376
Kind Code:
A
Abstract:
Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced localization within the intestines.
Inventors:
Gustavson, Linda Em
Srinivasan, Anansachari
Kasina, Sudar
Fritzburg, Alan Earl
Srinivasan, Anansachari
Kasina, Sudar
Fritzburg, Alan Earl
Application Number:
JP51010890A
Publication Date:
January 23, 1992
Filing Date:
June 15, 1990
Export Citation:
Assignee:
Neolex, corporation
International Classes:
A61K39/395; A61K51/00; A61K51/10; C07C323/60; C07D263/26; C07D309/08; C07D327/04; C07D307/18; C07F13/00; C07K5/06; C07K14/705; C07K14/715; C07K16/00; (IPC1-7): A61K39/395; A61K49/02; C07C323/60; C07D307/18; C07D309/08; C07F13/00; C07K15/28
Attorney, Agent or Firm:
Minoru Nakamura (7 outside)