Title:
【発明の名称】金属触媒及びその製造方法及び利用方法
Document Type and Number:
Japanese Patent JP2002542307
Kind Code:
A
Abstract:
Compounds having the formula: are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessary to complete a 3-12 membered heterocyclic ring; Z1 is an alkylene or arylene group; Q1 and Q2 are the same or different and are electron withdrawing groups; L1 and L3, taken together, represent -O-CR13-O-; L2 and L4, taken together, represent -O-CR14-O-; and R13 and R14 are the same or different and are selected from the group consisting of alkyl groups and aryl groups or R13 and R14 represent alkylene or arylene groups that are directly or indirectly bonded to one another. Methods for making such compounds are also disclosed, as are intermediates which can be used in their preparation. Also disclosed are methods for carrying out C-H insertion reactions using bis-transition metal catalysts, such as the above compounds. Procedures for preparing d-threo methylphenidate, tolterodine, CDP-840, nominfensine, and sertraline, are described.
Inventors:
Davies, Hugh, M. El.
Application Number:
JP2000613567A
Publication Date:
December 10, 2002
Filing Date:
April 26, 2000
Export Citation:
Assignee:
The Research Foundation of State University of New York
International Classes:
B01J31/18; B01J31/22; C07B53/00; C07B61/00; C07C67/343; C07C69/616; C07C69/618; C07C69/732; C07C69/757; C07D207/08; C07D207/277; C07F11/00; C07F13/00; C07F15/00; B01J23/46; C07D207/26; (IPC1-7): C07F15/00; B01J31/22; C07C67/343; C07C69/616; C07C69/618; C07C69/732; C07C69/757; C07D207/08
Other References:
JPN6010044160, ＳＥＴＳＵＮＥ，Ｊ． ｅｔ ａｌ, "Ｓｅｌｆ−Ａｓｓｅｍｂｌｅｄ Ｄｉｍｅｒｓ ｏｆ Ｃｏｐｐｅｒ（ＩＩ） Ｃｏｍｐｌｅｘｅｓ ｏｆ Ｔｒｉｐｏｄａｌ Ｄｉａｎｉｏｎｉｃ Ｌｉｇａｎｄｓ， ２−Ｐｙｒｉｄｙｌ−２，２’−ｄｉｐｙｒｒｏｌ", Ｉｎｏｒｇａｎｉｃ Ｃｈｅｍｉｓｔｒｙ, 1997, Ｖｏｌ．３６， Ｎｏ．２２, ｐ．５１３５−５１３７
JPN6010044162, ＫＩＴＡＭＵＲＡ，Ｃ． ｅｔ ａｌ, "Ｓｙｎｔｈｅｓｉｓ ａｎｄ ｒｅａｃｔｉｏｎｓ ｏｆ ３，３’−ｄｉｂｒｏｍｏｄｉｈｙｄｒｏｄｉｐｙｒｒｉｎｓ", Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ， Ｐｅｒｋｉｎ Ｔｒａｎｓａｃｔｉｏｎｓ １： Ｏｒｇａｎｉｃ ａｎｄ Ｂｉｏ−Ｏｒｇａｎｉｃ Ｃｈｅｍｉｓｔｒｙ, 1997, Ｎｏ．１０, ｐ．１４４３−１４４７
JPN6010044162, ＫＩＴＡＭＵＲＡ，Ｃ． ｅｔ ａｌ, "Ｓｙｎｔｈｅｓｉｓ ａｎｄ ｒｅａｃｔｉｏｎｓ ｏｆ ３，３’−ｄｉｂｒｏｍｏｄｉｈｙｄｒｏｄｉｐｙｒｒｉｎｓ", Ｊｏｕｒｎａｌ ｏｆ ｔｈｅ Ｃｈｅｍｉｃａｌ Ｓｏｃｉｅｔｙ， Ｐｅｒｋｉｎ Ｔｒａｎｓａｃｔｉｏｎｓ １： Ｏｒｇａｎｉｃ ａｎｄ Ｂｉｏ−Ｏｒｇａｎｉｃ Ｃｈｅｍｉｓｔｒｙ, 1997, Ｎｏ．１０, ｐ．１４４３−１４４７
Attorney, Agent or Firm:
Ken Takahashi