【発明の名称】新規なステロイド系有機物質結晶化方法およびそれによって得られる組成物

Title:

【発明の名称】新規なステロイド系有機物質結晶化方法およびそれによって得られる組成物

Document Type and Number:

Japanese Patent JP3281954

Kind Code:

B2

Abstract:

PCT No. PCT/FR91/00888 Sec. 371 Date Aug. 14, 1992 Sec. 102(e) Date Aug. 14, 1992 PCT Filed Nov. 12, 1991 PCT Pub. No. WO92/08730 PCT Pub. Date May 29, 1992.A process for crystallizing a pharmaceutically active steroidal product, without mechanical procedure, to obtain a homogeneous granulometric class which may be prepared beforehand, wherein the product which is desired to be crystallized is dissolved in a ternary mixture made of a lipophilic solvent, a hydrophilic solvent and a surface active agent at a temperature close to the boiling point of the mixture of solvents and wherein the mixture of solvents is allowed to revert to a temperature where the crystallization initiates, then, the thus-formed crystals are recovered.

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Inventors:

Lantern, Michel

Application Number:

JP50041592A

Publication Date:

May 13, 2002

Filing Date:

November 12, 1991

Export Citation:

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Assignee:

Laboratoire, Terramex, S, A

International Classes:

A61P5/00; A61P5/24; C07J1/00; C07J5/00; C07J7/00; C07J11/00; A61K31/56; (IPC1-7): C07J1/00; A61K31/56; A61P5/24; C07J5/00; C07J7/00; C07J11/00

Domestic Patent References:

JP1228502A
JP2279696A
JP4516326B1

Other References:

【文献】米国特許3836628(US,A)
【文献】Pharmceutisch Weekblad.Scientific Edition,4(1),5-
【文献】Polish Journal of Pharmacology and Pharmacy,29(2),

Attorney, Agent or Firm:

Michio Akaoka

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