Title:
【発明の名称】オキザリルアミノ酸誘導体およびそれを含有する医薬
Document Type and Number:
Japanese Patent JP2504874
Kind Code:
B2
Abstract:
The invention relates to oxalylamino acid derivatives of the formula I in which R and R' are identical or different and are C1-C6 -alkyl or hydrogen, R1 is hydrogen or C1-C4-alkyl, R2 is hydrogen, C1-C6-alkyl, C1-C3-alkoxy, carboxyl, C1-C6-alkoxycarbonyl, aryl, SH, NH2 or halogen, where the alkyl radicals are unsubstituted or substituted by aryl, OH, SH or NH2 or R1 and R2 together are a C2-C4-alkylene chain and the compounds in their predominantly pure D- and L-form and the physiologically tolerable salts. The compounds are distinguished as excellent inhibitors of prolyl hydroxylase and lysine hydroxylase.
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Inventors:
EKEHARUTO BAADAA
HAARARUTO BURUKUHARUTO
FUORUKUMARU GYUNTSURAA PUKARU
HAARARUTO BURUKUHARUTO
FUORUKUMARU GYUNTSURAA PUKARU
Application Number:
JP13326291A
Publication Date:
June 05, 1996
Filing Date:
May 10, 1991
Export Citation:
Assignee:
HOECHST AG
International Classes:
A61K31/16; A61K31/198; A61K31/215; A61K31/22; A61K31/223; A61K31/225; A61K31/395; A61K31/195; A61K31/401; A61P1/16; A61P37/00; A61P37/06; A61P43/00; C07C233/47; C07C233/56; C07C235/72; C07C323/59; C07D207/16; C12N9/99; (IPC1-7): A61K31/195; A61K31/215; A61K31/22; A61K31/225; C07C235/72; C12N9/99
Domestic Patent References:
| JP4310614B2 |
Attorney, Agent or Firm:
Chika Takagi (2 outside)