PURPOSE: To obtain the titled compound, by subjecting (Z,Z,Z,E,E)-polyprenyl alcohol derivative obtained from (E,E)-farnesylsulfone derivative and (Z,Z,Z)- isopulenoid to desulfonation and removal OH-protecting group.
CONSTITUTION: (E,E)-Farnesylsulfone derivative shown by the formula I (Ar is arryl) is reacted with a (Z,Z,Z)-isoprenoid shown by the formula II (X is halogen; R is OH-protecting group) to give a (Z,Z,Z,E,E)-polyprenyl alcohol derivative shown by the formula III. This compound is then reacted with a lithium-lower alkylamine, desulfonated, and the OH-protecting group is removed, to give a compound shown by the formula V.
USE: An intermediate for synthesizing drugs, polysaccharides useful as a food, peptidoglycan, glycoprotein, etc.
INOUE SEIICHI
MATSUHASHI TAISUKE
MIYAMOTO OSAMU
| JPS5430102A | 1979-03-06 |