Title:
TUMOR IMAGING COMPOUND
Document Type and Number:
Japanese Patent JP2009149678
Kind Code:
A
Abstract:
To provide novel amino acid compounds for use in detecting and evaluating brain and body tumors.
The amino acid compounds have a high specificity on the target site, when being in vivo administered, and for example, 2-amino-3-fluoro-2-methyl propane derivatives can be cited as preferable amino acid compounds, and the derivatives include a compound in which F of the derivatives is 18F. The invention further includes pharmaceutical compositions of an -amino acid moiety attached to any one of 4-, 5-, or 6-membered carbon rings. The labeled amino acid compounds are useful as an imaging agent in detecting and/or monitoring tumors in a subject by Positron Emission Tomography (PET) and Single Photon Emission Computer Tomography (SPECT).
Inventors:
GOODMAN MARK M
MCCONATHY JONATHAN
MCCONATHY JONATHAN
Application Number:
JP2009044923A
Publication Date:
July 09, 2009
Filing Date:
February 26, 2009
Export Citation:
Assignee:
UNIV EMORY
International Classes:
C07C229/20; G01T1/161; A61K51/00; A61K51/04; C07C229/22; C07C255/24; C07C271/22; C07D233/80; C07D291/04; C07F13/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita