TYK2 INHIBITOR AND USE OF THE SAME

Japanese Patent JP2022037224

A

To provide a compound, a composition thereof, and a method for using the compound and the composition for treating inhibition of TYK2, and TYK2-mediated disorder.SOLUTION: Provided is a compound, a composition thereof, and a method for using the compound and the composition for treating inhibition of TYK2 and TYK2-mediated disorder. The compound is also useful for research of TYK2 enzyme in a biological and pathological phenomenon; research of an intracellular signal transduction pathway which occurs in a body tissue; and in-vitro or in-vivo comparative evaluation of novel TYK2 inhibitor or kinase, signal transduction pathway, and other regulators of a cytokine level.SELECTED DRAWING: None

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JEREMY ROBERT GREENWOOD
GERALDINE C HARRIMAN
SILVANA MARCEL LEIT DE MORADEI
CRAIG E MASSE
THOMAS H MCLEAN
SAYAN MONDAL

JP2022000195A

March 08, 2022

January 04, 2022

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NIMBUS LAKSHMI INC

C07D471/04; A61K31/4439; A61K31/444; A61K31/5377; A61P1/04; A61P3/10; A61P5/00; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D401/14; C07D413/14; C07D417/14; C07D487/04; C07D519/00

JP2010522188A	2010-07-01
JP2015503622A	2015-02-02
JP2010516788A	2010-05-20
JP2009524670A	2009-07-02
JP2014500254A	2014-01-09
JP2016506368A	2016-03-03

WO2003057689A1

2003-07-17

Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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