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Title:
TAFIa阻害剤としての尿素及びスルファミド誘導体
Document Type and Number:
Japanese Patent JP5396279
Kind Code:
B2
Abstract:
The invention relates to compounds of the formula I as defined herein, which are inhibitors of activated thrombin-activatable fibrinolysis inhibitor. The compounds of the formula I are suitable for manufacturing medicaments for the prophylaxis, secondary prevention and therapy of one or more disorders which are associated with thromboses, embolisms, hypercoagulability or fibrotic changes.

Inventors:
Christopher Callus
Marc Blauenstrup
Werngart Cechticki
Andreas Evers
Marx Forman
Nis Halland
Hermann Schroider
Application Number:
JP2009539631A
Publication Date:
January 22, 2014
Filing Date:
November 22, 2007
Export Citation:
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Assignee:
SANOFI
International Classes:
C07C307/06; A61K31/197; A61K31/198; A61K31/215; A61K31/27; A61K31/36; A61K31/381; A61K31/40; A61K31/405; A61K31/407; A61K31/4184; A61K31/42; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/4465; A61K31/4468; A61P3/04; A61P3/10; A61P7/00; A61P7/02; A61P9/00; A61P9/10; A61P11/00; A61P19/02; A61P27/02; A61P29/00; A61P35/00; C07D207/06; C07D209/20; C07D211/58; C07D213/40; C07D213/73; C07D235/14; C07D261/08; C07D295/10; C07D317/58; C07D333/20; C07D487/08; C07K5/04; C07C275/16; C07C275/18; C07C275/24
Domestic Patent References:
JP2008515893A
JP2007533672A
JP2004506044A
JP2004506623A
Attorney, Agent or Firm:
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi



 
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