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Title:
CRTH2拮抗化合物の使用
Document Type and Number:
Japanese Patent JP2011503045
Kind Code:
A
Abstract:
The invention relates to compounds of general formula (I) wherein R1, R2, R3, R4 and R5 are as defined herein for the treatment of allergic conditions, wherein the treatment is by pulsed therapy which comprises a first period during which the compound is administered to the patient and a second period of at least seven days during which the compound is administered to the patient in a reduced amount.

Inventors:
Hunter Michael George
Petty fur eric roy
Perkins Colin Michael
Peyton Mark Anthony
Shwe Luchen
Application Number:
JP2010532660A
Publication Date:
January 27, 2011
Filing Date:
November 13, 2008
Export Citation:
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Assignee:
Oxagen Limited
International Classes:
C07D209/10; A61K31/404; A61K31/4439; A61K31/4709; A61P11/02; A61P11/06; A61P17/00; A61P37/08; A61P43/00; C07D401/06
Domestic Patent References:
JP2010500966A2010-01-14
JP2007509114A2007-04-12
JP2010500966A2010-01-14
Other References:
JPN7014000537; 'The Effects of OC000459 on Nasal Mediators' ClinicalTrials.gov Archive , 20060210
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi