疼痛に対するＬＥＰＲアゴニストの使用

Japanese Patent JP2023543409

A

本発明は、レプチン欠乏症またはレプチン抵抗性状態、例えば、脂肪異栄養症に苦しんでいる患者において、疼痛、オピオイドの使用および入院を低減するための方法を提供する。中枢神経系による疼痛の集中化または過敏化を伴う他の形態の慢性疼痛においても本発明の意義がありうる。TIFF2023543409000018.tif67157

JP2019534044	Anti-PD1 and anti-CTLA4 antibodies
WO/2023/100691	STEM CELL PROLIFERATION PROMOTER
JP2002530117	INDUSTRIAL APPLICABILITY The use of activated TRAP for screening specific inhibitors of TRAP and ancillary methods for compound identification for the treatment of diseases or degenerative conditions that cause increased bone resorption.

Oral Elif Alioglu
Akinji Baris
Foz de Freitas Maria Cristina

JP2023516678A

October 16, 2023

September 15, 2021

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REGENERON PHARMACEUTICALS, INC.

A61K45/00; A61K31/485; A61K39/395; A61K45/06; A61P1/00; A61P1/08; A61P1/16; A61P1/18; A61P25/04; A61P25/22; A61P25/24; A61P29/02; A61P43/00

Hatsushi Shimizu
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Kousuke Umemura
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Maki Shioda
Kazuya Kawamoto

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