Title:
【発明の名称】ヒトの黄斑変性を治療するための純粋なゼアキサンチンの3R-3’R立体異性体
Document Type and Number:
Japanese Patent JPH10512594
Kind Code:
A
Abstract:
Methods and formulations are disclosed for making and purifying the 3R-3R' stereoisomer of zeaxanthin as a sole detectable isomer for use as a drug or vitamin by humans, specifically for the treatment of patients suffering from macular degeneration. Zeaxanthin preparations containing only the desired 3R-3R' stereoisomer can be produced by a strain of Flavobacterium multivorum (ATCC accession number 55238). After synthesis using microbial fermentation, the zeaxanthin can be concentrated to a level of 5 to 20 percent (by weight) using simple and inexpensive means such as solvent extraction. It can also be purified to much higher levels by other methods if desired.
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Inventors:
Garnet, kevin m
Dennis El, Gear Heart
Gala Santos, Luis H
Dennis El, Gear Heart
Gala Santos, Luis H
Application Number:
JP51758397A
Publication Date:
December 02, 1998
Filing Date:
October 30, 1996
Export Citation:
Assignee:
Applied Food Biotechnology Incorporated
International Classes:
A23L1/30; A61F9/00; A61K9/107; A61K9/48; A61K31/015; C12P23/00; A61K31/047; A61K31/07; A61P27/02; C12R1/20; (IPC1-7): A61K31/015; A61K9/107; C12P23/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)