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Title:
beta-L-2'-DEOXY-NUCLEOSIDE FOR TREATMENT OF HEPATITIS B
Document Type and Number:
Japanese Patent JP2007269798
Kind Code:
A
Abstract:

To provide a new treating agent of infection with hepatitis B virus.

The pharmaceutical composition contains β-L-2'-deoxycytidine exemplified by the compound of the formula [wherein, R is selected from the group consisting of H, a straight chained, a branched or cyclic alkyl, a CO-alkyl, a CO-aryl, a CO-alkoxyalkyl, a CO-aryloxyalkyl, a CO-substituted aryl, an alkylsulfonyl, an arylsulfonyl, an aralkylsulfonyl, an amino acid residue, mono, di, or triphosphate, or a phosphate derivative; and BASE is a purine or pyrimidine base which may be optionally substituted].

COPYRIGHT: (C)2008,JPO&INPIT


Inventors:
GOSSELIN GILLES (FR)
IMBACH JEAN-LOUIS (FR)
BRYANT MARTIN L (US)
Application Number:
JP2007122896A
Publication Date:
October 18, 2007
Filing Date:
May 07, 2007
Export Citation:
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Assignee:
IDENIX CAYMAN LTD (KY)
CENTRE NAT RECH SCIENT (FR)
IMBACH JEAN LOUIS (FR)
BRYANT MARTIN L (US)
GOSSELIN GILLES (FR)
International Classes:
A61K31/7068; C07H19/073; A61K9/20; A61K9/48; A61K31/513; A61K31/522; A61K31/662; A61K31/70; A61K31/7042; A61K31/7052; A61K31/7064; A61K31/7072; A61K31/7076; A61K31/708; A61P1/16; A61P31/12; A61P31/20; C07H19/06; C07H19/10; C07H19/16; C07H19/173; C07H19/20
Foreign References:
WO1992008727A11992-05-29
WO1996040164A11996-12-19
Attorney, Agent or Firm:
Takashi Ishida
Jun Tsuruta
Fukumoto product