A high polymer film and the antiadhesive material using it

Japanese Patent JP6239771

B2

An object of the present invention is to provide a polymer film that can be adjusted to movement or a fine uneven surface of a living body and has excellent ability to adhere to a biological tissue. The present invention provides a polymer film, comprising a block copolymer having a structure in which branched polyalkylene glycol and polyhydroxyalkanoic acid are bound to each other, wherein the polymer film has a film thickness of 10 to 1000 nm. The branched polyalkylene glycol has at least three terminal hydroxyl groups per molecule, the mass percentage of the branched polyalkylene glycol relative to the total mass of the block copolymer is 1% to 30%, and a value obtained by dividing the average molecular weight of polyhydroxyalkanoic acid in the block copolymer by X that is the number of terminal hydroxyl groups present per a single molecule of the branched polyalkylene glycol is 10000 to 30000.

Akihiro Saito
Toru Arakane
Kazuhiro Tanahashi
Takeshi Okabayashi
Shinji Takeoka
Toshinori Fujieda
Shoichiro Suzuki
Atsushi Murata
Shinya Otsubo

JP2016544650A

November 29, 2017

June 17, 2016

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TORAY INDUSTRIES,INC.
Nano Theta Co., Ltd.

C08G63/06; A61L15/12; A61L27/18; A61L31/06; A61P41/00; B32B27/36; C08G63/664; C08G65/332; C08J5/18

JP2008222768A
JP2008106269A
JP2014171590A
JP2009029967A

Tzong-Der Way et al,Preparation and characterization of branched polymers as postperative anti-adhesion barriers,Applied surface Science,2009年12月21日,Volume 256, Issue 10,pp. 3330-3336

Yusuke Hiraki
Satoshi Fujita
Wakako Nomura

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