2-ALKYLCYSTEINAMIDE OR SALT THEREOF, PROCESS FOR PRODUCING THESE, AND USE OF THESE

Title:

2-ALKYLCYSTEINAMIDE OR SALT THEREOF, PROCESS FOR PRODUCING THESE, AND USE OF THESE

Document Type and Number:

WIPO Patent Application WO/2004/090152

Kind Code:

A1

Abstract:

A process for producing a 2-alkylcysteinamide represented by the general formula (1) or a salt thereof, which comprises hydrolyzing a 4-alkylthiazolidine-4-carboxamide represented by the general formula (2) or a salt thereof. (In the general formula (1), R represents C_1-4 alkyl.) (In the general formula (2), R represents C_1-4 alkyl; and R₁ and R₂ each independently represents hydrogen or C_1-4 alkyl or R₁ is bonded to R₂ to form a C_4-7 alicyclic structure, provided that not both of R₁ and R₂ are hydrogen.) Either cells of a microorganism having the ability to stereoselectively hydrolyzing a 2-alkyl-L-cysteinamide or a substance obtained by treating the cells is caused to act on the compound of the general formula (1) to yield a 2-alkyl-L-cysteine.

Inventors:

HIGUCHI YASUSHI (JP)
TANAKA AKINORI (JP)
HASEMI RYUJI (JP)

Application Number:

PCT/JP2004/004988

Publication Date:

October 21, 2004

Filing Date:

April 07, 2004

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MITSUBISHI GAS CHEMICAL CO (JP)
HIGUCHI YASUSHI (JP)
TANAKA AKINORI (JP)
HASEMI RYUJI (JP)

International Classes:

C07C319/02; C07C319/06; C07C323/60; C12P13/12; C12P41/00; (IPC1-7): C12P41/00

Foreign References:

JP2001328970A	2001-11-27
JP2002315597A	2002-10-29
JPS5714573A	1982-01-25

Other References:

BRANT L. ET AL: "Thiazoline ring formation from 2-methylcysteines and 2-halomethylalanines", HETEROCYCLES, vol. 58, 2002, pages 601 - 634, XP002980831
DUNKERTON L.V.: "Synthesis of potential anti-vesicant compounds", AD REP., vol. AD-B-161803, 1992, pages 1 - 49, XP002980829

Attorney, Agent or Firm:

Ide, Masatake (9F Gobancho Grand Bldg., 3-1, Gobanch, Chiyoda-ku Tokyo, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: METHOD FOR EXTRACTING COLLAGEN COMPRISING MICROBIAL FERMENTATION

Next Patent: POLYMERASE INHIBITOR AND METHOD OF USING SAME