Title:
3,4-DIHYDROQUINOLIN-2-ONE, 5,6-FUSED OXAZIN-3-ONE, AND 5,6-FUSED THIAZIN-3-ONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS
Document Type and Number:
WIPO Patent Application WO2004014389
Kind Code:
A8
Abstract:
This invention provides compounds defined by Formula (I), or a pharmaceutically acceptable salt thereof, wherein R<1>, Q, Y, Y<5>, Y<6>, Y<8>, R<2>, R<2a>, and R<4> are as defined in the specification. The invention also provides pharmaceutical compositions comprising a compound of Formula (I) and the use of the compounds of Formula (I) as matrix metalloproteinase inhibitors.
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Inventors:
O'BRIEN PATRICK MICHAEL (US)
Application Number:
PCT/IB2003/003537
Publication Date:
April 29, 2004
Filing Date:
August 04, 2003
Export Citation:
Assignee:
WARNER LAMBERT CO (US)
O'BRIEN PATRICK MICHAEL (US)
O'BRIEN PATRICK MICHAEL (US)
International Classes:
A61P29/00; C07D215/48; C07D265/36; C07D279/16; C07D401/12; C07D405/06; C07D413/12; C07D417/06; C07D417/14; C07D471/04; C07D498/04; C07D513/04; (IPC1-7): A61K31/5415; C07D265/36; C07D279/16; C07D417/14; C07D413/12; C07D417/06; C07D215/22; C07D401/12; C07D498/04; C07D513/04; C07D471/04; C07D405/06; A61P29/00; A61K31/4375; A61K31/4704; A61K31/4709; A61K31/538; A61K31/5383; A61K31/542
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