Title:
4-CARBONYLAMINO ISOINDOLIN-1-ONE DERIVATIVE, COMPOSITION COMPRISING SAME, AND USE METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/236926
Kind Code:
A1
Abstract:
A 4-carbonylamino isoindolin-1-one compound represented by formula (I), or an optical isomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate (such as a hydrate) thereof, or an inclusion compound thereof, or a racemate thereof, or an isotope marker thereof, or a nitrogen oxide thereof, and a pharmaceutical composition and use thereof. The compound has good anti-multiple myeloma activity, and can effectively treat and/or prevent the growth and reproduction of multiple myeloma.
Inventors:
GAO QINGZHI (CN)
LIU SHENGNAN (CN)
GAO XIANGQIAN (CN)
ZHANG SHUNJIE (CN)
ZHANG XIANGRUI (CN)
DU JINPING (CN)
YANG LIU (CN)
LI YANG (CN)
ZHU XIAOLING (CN)
HAN JIANBIN (CN)
LIU SHENGNAN (CN)
GAO XIANGQIAN (CN)
ZHANG SHUNJIE (CN)
ZHANG XIANGRUI (CN)
DU JINPING (CN)
YANG LIU (CN)
LI YANG (CN)
ZHU XIAOLING (CN)
HAN JIANBIN (CN)
Application Number:
PCT/CN2023/098489
Publication Date:
December 14, 2023
Filing Date:
June 06, 2023
Export Citation:
Assignee:
TIANJIN GUDUI BIO PHARM CO LTD (CN)
International Classes:
A61K31/454; C07D401/04; A61P35/00
Domestic Patent References:
| WO2019218904A1 | 2019-11-21 |
Foreign References:
| CN109705044A | 2019-05-03 | |||
| US20170319708A1 | 2017-11-09 | |||
| CN111285850A | 2020-06-16 | |||
| CN107739389A | 2018-02-27 | |||
| US20170056510A1 | 2017-03-02 |
Attorney, Agent or Firm:
BEIJING TANLULAI PATENT AGENT LTD et al. (CN)
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