Title:
4-CARBONYLAMINOISOINDOLINE-1,3-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/236927
Kind Code:
A1
Abstract:
A 4-carbonylaminoisoindoline-1,3-dione compound as represented by formula (I), or an optical isomer, pharmaceutically-acceptable salt, solvate (such as hydrate), inclusion compound, racemate, isotopic marker, or nitrogen oxide thereof; and a pharmaceutical composition and use thereof. The compound has good activity of resisting multiple myeloma and can effectively treat and/or prevent growth of the multiple myeloma.
Inventors:
GAO QINGZHI (CN)
LIU SHENGNAN (CN)
HAN JIANBIN (CN)
ZHANG SHUNJIE (CN)
ZHANG XIANGRUI (CN)
LIU YANG (CN)
ZHANG TINGTING (CN)
LI YANG (CN)
ZHU XIAOLING (CN)
GAO XIANGQIAN (CN)
LIU SHENGNAN (CN)
HAN JIANBIN (CN)
ZHANG SHUNJIE (CN)
ZHANG XIANGRUI (CN)
LIU YANG (CN)
ZHANG TINGTING (CN)
LI YANG (CN)
ZHU XIAOLING (CN)
GAO XIANGQIAN (CN)
Application Number:
PCT/CN2023/098491
Publication Date:
December 14, 2023
Filing Date:
June 06, 2023
Export Citation:
Assignee:
TIANJIN GUDUI BIO PHARM CO LTD (CN)
International Classes:
C07D401/04; A61K31/454; A61P35/00
Domestic Patent References:
| WO2019218904A1 | 2019-11-21 |
Foreign References:
| US20170319708A1 | 2017-11-09 | |||
| CN111285850A | 2020-06-16 | |||
| CN109705044A | 2019-05-03 | |||
| CN107739389A | 2018-02-27 | |||
| US20170056510A1 | 2017-03-02 |
Attorney, Agent or Firm:
BEIJING TANLULAI PATENT AGENT LTD et al. (CN)
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