5-(ARYLSULFONYL)-PYRAZOLOPIPERIDINES

Title:

5-(ARYLSULFONYL)-PYRAZOLOPIPERIDINES

Document Type and Number:

WIPO Patent Application WO2007064914

Kind Code:

A8

Abstract:

The invention provides N-cyclic sulfonamido compounds of Formula (I) wherein A, B, R₁, R_1a, R₂, R_2a, R₃ and R_3a are as described in the specification. Compounds of Formula (I) are useful in treating or preventing cognitive disorders, such as Alzheimer 's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I), methods of preparing compounds of formula (I), and methods of treating cognitive disorders, such as Alzheimer's disease.

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Inventors:

GAROFALO ALBERT W (US)
JAGODZINSKI JACEK J (US)
KONRADI ANDREI W (US)
SEMKO CHRISTOPHER M (US)
SMITH JENIFER L (US)
XU YING-ZI (US)
YE XIAOCONG MICHAEL (US)

Application Number:

PCT/US2006/046039

Publication Date:

May 15, 2008

Filing Date:

December 01, 2006

Export Citation:

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Assignee:

ELAN PHARM INC (US)
GAROFALO ALBERT W (US)
JAGODZINSKI JACEK J (US)
KONRADI ANDREI W (US)
SEMKO CHRISTOPHER M (US)
SMITH JENIFER L (US)
XU YING-ZI (US)
YE XIAOCONG MICHAEL (US)

International Classes:

C07D211/96; C07D471/04; C07D491/04

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