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Title:
5' CHOLINE PHOSPHATE 3'-AZIDO 3'-DEOXYTHYMIDINE
Document Type and Number:
WIPO Patent Application WO/2004/011480
Kind Code:
A1
Abstract:
The invention relates to a novel composition 5' choline phosphate 3'-azido 3'-deoxythymidine of formula (I) which exhibits an antiviral action, first and foremost against a human immunodefficient virus (HIV). Said composition can be produced by two ways: by condensation of 3'-azido 3'- deoxythymidine (AZT, II) with choline phosphate, or by interaction between monophosphate AZT (III) and choline.

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Inventors:
SHIPITSYN ALEXANDER VALER EVIC (RU)
YASKO MAXIM VLADIMIROVICH (RU)
SHIROKOVA ELENA ANATOL EVNA (RU)
KOUKHANOVA MARINA KONSTANTINOV (RU)
PRONAYEVA TATIANA RUDOLFOVNA (RU)
FEDUK NINA VLADIMIROVNA (RU)
POKROVSKY ANDREY GEORGIEVICH (RU)
GOSSELIN GILLES (FR)
PERIGAUD CHRISTIAN (FR)
Application Number:
PCT/RU2003/000331
Publication Date:
February 05, 2004
Filing Date:
July 25, 2003
Export Citation:
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Assignee:
ZAKRYTOE AKTSIONERNOE OBSHCEST (RU)
SHIPITSYN ALEXANDER VALER EVIC (RU)
YASKO MAXIM VLADIMIROVICH (RU)
SHIROKOVA ELENA ANATOL EVNA (RU)
KOUKHANOVA MARINA KONSTANTINOV (RU)
PRONAYEVA TATIANA RUDOLFOVNA (RU)
FEDUK NINA VLADIMIROVNA (RU)
POKROVSKY ANDREY GEORGIEVICH (RU)
GOSSELIN GILLES (FR)
PERIGAUD CHRISTIAN (FR)
International Classes:
A61P31/12; C07H19/10; (IPC1-7): C07H19/10; A61K31/706; A61P31/12
Foreign References:
RU2106353C11998-03-10
RU2104282C11998-02-10
US4724232A1988-02-09
Attorney, Agent or Firm:
Mesyashnaya, Nataliya Vitalievna (Moscow, RU)
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