5-LIPOXYGENASE INHIBITORS - SMITHKLINE BEECHAM CORP

Title:

5-LIPOXYGENASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO1991014674

Kind Code:

A3

Abstract:

Hydroxyurea compounds comprising substituted and unsubstituted 1,2,3,4-tetrahydronaphthalene, indane, dihydrobenzofuran, 4H-2,3-dihydrobenzopyran, dihydrobenzothiophene, and indoline derivatives, pharmaceutical compositions containing said compounds, and their use as analgesics and 5-lipoxygenase pathway inhibitors.

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Inventors:

ADAMS JERRY LEROY (US)
GARIGIPATI RAVI SHANKER (US)
GRISWOLD DON EDGAR (US)
SCHMIDT STANLEY JAMES (US)

Application Number:

PCT/US1991/002010

Publication Date:

January 09, 1992

Filing Date:

March 25, 1991

Export Citation:

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Assignee:

SMITHKLINE BEECHAM CORP (US)

International Classes:

A61K31/16; A61K31/17; A61K31/27; A61K31/275; A61K31/34; A61K31/343; A61K31/415; A61K31/4184; A61K31/47; A61P9/08; A61P9/10; A61P11/00; A61P17/00; A61P25/00; A61P25/04; A61P27/02; A61P27/14; A61P27/16; A61P29/00; A61P37/00; A61P37/08; A61P43/00; C07C259/06; C07C275/64; C07D213/30; C07D215/14; C07D215/42; C07D235/12; C07D307/82; (IPC1-7): C07C275/64; A61K31/17; A61K31/34; A61K31/44; A61K31/47; C07C239/12; C07D213/30; C07D215/14; C07D235/12; C07D307/82

Foreign References:

US4873259A

1989-10-10

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