Title:
ACYL PIPERAZINE DERIVATIVES AS TTX-S BLOCKERS
Document Type and Number:
WIPO Patent Application WO/2012/020567
Kind Code:
A1
Abstract:
The present invention relates to acyl piperazine derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
Inventors:
MORITA MIKIO (JP)
WATANABE SHUZO (JP)
WATANABE SHUZO (JP)
Application Number:
PCT/JP2011/004515
Publication Date:
February 16, 2012
Filing Date:
August 09, 2011
Export Citation:
Assignee:
RAQUALIA PHARMA INC (JP)
MORITA MIKIO (JP)
WATANABE SHUZO (JP)
MORITA MIKIO (JP)
WATANABE SHUZO (JP)
International Classes:
C07D239/47; A61K31/506; A61P25/00; A61P25/04; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P43/00; C07D401/14; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12
Domestic Patent References:
| WO2008147864A2 | 2008-12-04 |
Foreign References:
| JP2008540443A | 2008-11-20 | |||
| EP1645556A1 | 2006-04-12 |
Other References:
DATABASE CHEMCATS 9 March 2011 (2011-03-09), "Chemical Name:Methanone, cyclopropyl[hexahydro-4-(6-methoxy-4-pyrimidi nyl)-lH-1,4-diazepin-1-yl]", accession no. STN Database accession no. 0062607277
Attorney, Agent or Firm:
IWATANI, Ryo (1-31 Dojima 2-chome, Kita-ku, Osaka-sh, Osaka 03, JP)
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