Title:
AGENT FOR PREVENTING OR TREATING MUSCULAR DISEASE
Document Type and Number:
WIPO Patent Application WO/2022/014703
Kind Code:
A1
Abstract:
In the present invention, a myoregulin inhibitor such as a myoregulin antisense oligonucleotide or anti-myoregulin antibody is employed as an active component of an agent for preventing or treating a muscular disease such as muscular dystrophy, inclusion body myositis, amyotrophic lateral sclerosis, disuse muscle atrophy, and sarcopenia.
Inventors:
ISHIKAWA KIYOSHI (JP)
MURATA SHUMPEI (JP)
MURATA SHUMPEI (JP)
Application Number:
PCT/JP2021/026798
Publication Date:
January 20, 2022
Filing Date:
July 16, 2021
Export Citation:
Assignee:
MITSUBISHI TANABE PHARMA CORP (JP)
International Classes:
A61K45/00; A61K31/7088; A61K48/00; A61P21/00; A61P25/00; A61P29/00; C12N15/113
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| WO2020100826A1 | 2020-05-22 | |||
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Foreign References:
| JP2017214337A | 2017-12-07 | |||
| US20160228502A1 | 2016-08-11 | |||
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| JPH0373280B2 | 1991-11-21 | |||
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Other References:
ANDERSON, DOUGLAS M. ET AL.: "A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance", CELL, vol. 160, 2015, pages 595 - 606, XP029139829, Retrieved from the Internet DOI: 10.1016/j.cell.2015.01.009
AM J PHYSIOL CELL PHYSIOL., vol. 308, no. 9, pages C699 - 709
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
ZHANGMADDEN, GENOME RES, vol. 7, 1997, pages 649 - 656
SMITHWATERMAN, ADV. APPL. MATH., vol. 2, 1981, pages 482 - 489
CHATTOPADHYAYA ET AL., J. ORG. CHEM., vol. 74, 2009, pages 118 - 134
EXP.OPIN.THER.PATENTS, vol. 6, no. 5, 1996, pages 441 - 456
KOEHLERMILSTEIN ET AL., NATURE, vol. 256, 1975, pages 495 - 497
EXPERIMENTAL MEDICINE (EXTRA ISSUE, vol. 6, no. 10, 1988
NATURE GENETICS, vol. 15, 1997, pages 146 - 156
NATURE GENETICS, vol. 7, 1994, pages 13 - 21
NATURE, vol. 368, 1994, pages 856 - 859
NATURE, vol. 348, 1990, pages 552 - 554
"Phage display a laboratory manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
"Antibody Engineering - a Practical Approach", 1996, IRL PRESS
AM J PHYSIOL CELL PHYSIOL., vol. 308, no. 9, pages C699 - 709
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
ZHANGMADDEN, GENOME RES, vol. 7, 1997, pages 649 - 656
SMITHWATERMAN, ADV. APPL. MATH., vol. 2, 1981, pages 482 - 489
CHATTOPADHYAYA ET AL., J. ORG. CHEM., vol. 74, 2009, pages 118 - 134
EXP.OPIN.THER.PATENTS, vol. 6, no. 5, 1996, pages 441 - 456
KOEHLERMILSTEIN ET AL., NATURE, vol. 256, 1975, pages 495 - 497
EXPERIMENTAL MEDICINE (EXTRA ISSUE, vol. 6, no. 10, 1988
NATURE GENETICS, vol. 15, 1997, pages 146 - 156
NATURE GENETICS, vol. 7, 1994, pages 13 - 21
NATURE, vol. 368, 1994, pages 856 - 859
NATURE, vol. 348, 1990, pages 552 - 554
"Phage display a laboratory manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
"Antibody Engineering - a Practical Approach", 1996, IRL PRESS
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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