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Title:
AGONISTS OF GUANYLATE CYCLASE USEFUL FOR DOWNREGULATION OF PRO-INFLAMMATORY CYTOKINES
Document Type and Number:
WIPO Patent Application WO/2015/054500
Kind Code:
A3
Abstract:
This invention provides a method to prevent, control, and/or treat an inflammatory disease or disorder by administering at least one agonist of guanalyte cyclase receptor, or pharmaceutical compositions thereof, either alone or either concurrently or sequentially with another compound or an active agent used to treat the disease or disorder, and/or with an inhibitor of cGMP-dependent phosphodieasterases.

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Inventors:
SHAILUBHAI KUNWAR (US)
Application Number:
PCT/US2014/059914
Publication Date:
June 11, 2015
Filing Date:
October 09, 2014
Export Citation:
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Assignee:
SYNERGY PHARMACEUTICALS INC (US)
International Classes:
A61K38/10; A61K38/08; C07K7/08; C07K14/435
Foreign References:
US20100221329A12010-09-02
US20030170223A12003-09-11
US20130210822A12013-08-15
Other References:
See also references of EP 3065757A4
Attorney, Agent or Firm:
ELRIFI, Ivor et al. (1299 Pennsylvania Avenue N.W.,Suite 70, Washington District of Columbia, US)
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