Title:
AMINE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONIST ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2007/125952
Kind Code:
A1
Abstract:
Disclosed is a compound represented by the formula (I) below, a pharmaceutically
acceptable salt thereof, or a solvate of any of them. (I) In the formula, R1
represents an optionally substituted lower alkyl group; Y represents -S(O)n-
(wherein n is 1 or 2) or -CO-; R2 represents a hydrogen or a lower alkyl;
R7 represents a hydrogen or a lower alkyl; X represents a lower alkylene,
a lower alkenylene, an arylene, a cycloalkylene or the like; and Z represents
a lower alkyl, an optionally substituted hydrocarbon ring group, an optionally
substituted heterocyclic group or the like.
Inventors:
OKUNO TAKAYUKI (JP)
KOUYAMA NAOKI (JP)
SAKAGAMI MASAHIRO (JP)
KOUYAMA NAOKI (JP)
SAKAGAMI MASAHIRO (JP)
Application Number:
PCT/JP2007/058938
Publication Date:
November 08, 2007
Filing Date:
April 25, 2007
Export Citation:
Assignee:
SHIONOGI & CO (JP)
OKUNO TAKAYUKI (JP)
KOUYAMA NAOKI (JP)
SAKAGAMI MASAHIRO (JP)
OKUNO TAKAYUKI (JP)
KOUYAMA NAOKI (JP)
SAKAGAMI MASAHIRO (JP)
International Classes:
C07C311/05; A61K31/18; A61K31/381; A61K31/40; A61K31/415; A61K31/4164; A61K31/4184; A61K31/42; A61K31/423; A61K31/425; A61K31/426; A61K31/427; A61K31/428; A61K31/437; A61K31/44; A61K31/4402; A61K31/4409; A61K31/4436; A61K31/4439; A61K31/4453; A61K31/451; A61K31/47; A61K31/472; A61K31/473; A61K31/495; A61K31/4965; A61K31/50; A61K31/501; A61K31/502; A61K31/505; A61K31/5375; A61K31/538; A61K31/553; A61P3/04; A61P9/04; A61P9/12; A61P15/00; A61P25/08; A61P25/20; A61P25/24; A61P43/00; C07C311/07; C07C317/36; C07D207/325; C07D211/14; C07D213/38; C07D213/74; C07D213/82; C07D215/38; C07D217/04; C07D217/14; C07D217/22; C07D219/10; C07D231/38; C07D233/61; C07D235/30; C07D237/20; C07D237/22; C07D237/34; C07D239/42; C07D241/20; C07D261/14; C07D261/20; C07D263/58; C07D265/30; C07D265/36; C07D267/14; C07D275/02; C07D277/28; C07D277/62; C07D277/82; C07D295/12; C07D295/18; C07D333/36; C07D333/40; C07D333/66; C07D333/72; C07D403/04; C07D409/04; C07D413/04; C07D417/12; C07D498/04; C07D513/04
Domestic Patent References:
| WO2007002126A1 | 2007-01-04 | |||
| WO2001037826A1 | 2001-05-31 | |||
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| WO2007002126A1 | 2007-01-04 | |||
| WO2006001318A1 | 2006-01-05 | |||
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Foreign References:
| JP2003503486A | 2003-01-28 | |||
| JP2004501120A | 2004-01-15 | |||
| JP2002541245A | 2002-12-03 | |||
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Other References:
PEPTIDES, vol. 18, 1997, pages 445
TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 18, 1997, pages 372
PEPTIDES, vol. 18, 1997, pages 445
INUI, A. ET AL., ENDOCRINOLOGY, vol. 131, 1992, pages 2090 - 2096
See also references of EP 2017261A4
TRENDS IN PHARMACOLOGICAL SCIENCES, vol. 18, 1997, pages 372
PEPTIDES, vol. 18, 1997, pages 445
INUI, A. ET AL., ENDOCRINOLOGY, vol. 131, 1992, pages 2090 - 2096
See also references of EP 2017261A4
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (Intellectual Property Department,12-4, Sagisu 5-chome,Fukushima-ku, Osaka-shi, Osaka02, JP)
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