ANTI-CANCER PRODRUG FOR OVERCOMING MULTIDRUG RESISTANCE

Title:

ANTI-CANCER PRODRUG FOR OVERCOMING MULTIDRUG RESISTANCE

Document Type and Number:

WIPO Patent Application WO/2021/118329

Kind Code:

A2

Abstract:

The present invention relates to an anti-cancer prodrug comprising a compound represented by [Formula 1] as stated below: The anti-cancer prodrug, according to the present invention, has high selectivity for cancer cells overexpressing COX-2, and selectively reacts to H2O2 and effectively releases two drugs, thereby overcoming multidrug resistance and improving anti-cancer effects.

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Inventors:

KIM JONG SEUNG (KR)
JANGILI PARAMESH (KR)
WON MIAE (KR)
SHIM INSEOB (KR)
SHIN JINWOO (KR)
REN WEN XIU (KR)
KANG CHULHUN (KR)

Application Number:

PCT/KR2020/018292

Publication Date:

June 17, 2021

Filing Date:

December 14, 2020

Export Citation:

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Assignee:

UNIV KOREA RES & BUS FOUND (KR)

International Classes:

C07F5/02

Attorney, Agent or Firm:

JUNG, Eun Youl et al. (KR)

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